Optimizing Pertussis Control Among Young Infants

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Pertussis in Young Infants Throughout the World

In typical pertussis in young infants, the child will appear deceptively well; he or she will have coryza, sneezing, and a mild cough. There is no fever. This progresses to gagging, gasping, eye bulging, bradycardia, cyanosis, and vomiting. There is leukocytosis with lymphocytosis and apneic episodes. Deaths relate to leukocytosis, pulmonary hypertension, and pneumonia. The source of pertussis ...

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Strategies to control pertussis in infants.

The UK is currently in the midst of a large outbreak of pertussis, with the highest morbidity and mortality occurring in young unimmunised infants. This review considers the potential strategies to optimise control of pertussis in infants, including vaccination of (1) adolescents, (2) close household contacts of newborn infants (cocooning), (3) newborn infants and (4) pregnant women. The paper ...

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ژورنال

عنوان ژورنال: Clinical Infectious Diseases

سال: 2015

ISSN: 1058-4838,1537-6591

DOI: 10.1093/cid/civ077